Ketamine Infusion vs. Ketamine-Assisted Psychotherapy: Key Differences

If you’ve been exploring ketamine treatment, you may have noticed two very different options: ketamine infusions and ketamine-assisted psychotherapy (KAP). Both involve the same medicine, but the way they’re offered—and what you take away from them—can feel very different.

What Is a Ketamine Infusion?

A ketamine infusion usually happens in a medical setting, often supervised by a nurse or physician. The focus is on the medicine itself—delivered through an IV drip, with vital signs monitored throughout. Infusions can provide rapid symptom relief, especially for depression, but the emphasis is more on the biological effect of ketamine than on the therapeutic process that surrounds it.

What Is Ketamine-Assisted Psychotherapy (KAP)?

KAP combines ketamine with a therapeutic relationship. Instead of receiving the medicine in a purely medical context, you’re guided by a therapist trained to support the emotional and psychological aspects of the experience. The session is designed not just for symptom relief but also for exploration, insight, and integration—helping you connect what arises during the session to meaningful changes in daily life.

The Role of Therapy and Integration

This is where the biggest difference lies. Infusions may give temporary relief, but without support for processing what comes up, the effects can fade quickly. KAP, by weaving in therapy before, during, and after sessions, helps turn the experience into something that creates longer-term growth.

Choosing What’s Right for You

Neither approach is “better” for everyone. Infusions may be right for someone looking for rapid relief under medical supervision. KAP may be better suited for those who want a therapeutic container, deeper self-understanding, and integration of insights into ongoing healing.

Both approaches use the same medicine, but the experience and outcomes can feel very different. Understanding these differences can help you make a choice that aligns with your needs and your goals for healing.